TG100–115 is a PI3K γ and -δ inhibitor (IC50 = 83 and 235 nM, respectively).
Model structure of human PI3Kγ kinase (ribbon) with TG100-115 located in the catalytic domain.
TG100–115 is a PI3K γ and -δ inhibitor (IC50 = 83 and 235 nM, respectively).
Model structure of human PI3Kγ kinase (ribbon) with TG100-115 located in the catalytic domain.