Name :
Proinsulin/INS (Human) Recombinant Protein
Biological Activity :
Human Proinsulin/INS (NP_000198, 25 a.a. – 110 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins
Tag :
Result of bioactivity analysis
Protein Accession No. :
NP_000198
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=3630
Amino Acid Sequence :
Molecular Weight :
11.8
Storage and Stability :
Stored at 2°C to 8°C for 1 week.For long term storage, aliquot and store at -20°C to -80°C.Avoid repeated freezing and thawing cycles.
Host :
Human
Interspecies Antigen Sequence :
Preparation Method :
Escherichia coli expression system
Purification :
Quality Control Testing :
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Storage Buffer :
In PBS, pH 7.4 (10% glycerol)
Applications :
SDS-PAGE，
Gene Name :
INS
Gene Alias :
ILPR, IRDN
Gene Description :
insulin
Gene Summary :
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5′ region and with the IGF2 gene at the 3′ region. [provided by RefSeq
Other Designations :
OTTHUMP00000011161|OTTHUMP00000011162|OTTHUMP00000196038|proinsulin
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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