Product Name :
NSC348884
Synonym :
Chemical Name :
CAS NO.:
81624-55-7
Molecular formula :
C38H40N10
Molecular Weight:
636.79 g/mol
Classification :
MedChemExpress Products > Life Sciences > NSC348884
Description:
NSC348884 is a novel anti-cancer drug that is an inhibitor of RNA polymerase. It has been shown to inhibit cellular transformation and viability in human leukemia HL-60 cells and prostate cancer cells, as well as inducing apoptosis. The mechanism of action of NSC348884 may be mediated through the induction of reactive oxygen species (ROS), activation of caspases, and modulation of signal transduction pathways. NSC348884 has also been shown to induce a variety of transcriptional effects on tumor cells, including upregulation or downregulation of genes involved in cell cycle regulation and apoptosis. This drug is also efficacious against brain tumors with malignant characteristics and breast cancer cells that are resistant to monoclonal antibody therapy.
Purity :
>98%
Specifications :
10 mM * 1 mL
Price.:
100
Price unit :
$
Inventory :
In stock
Related websites: https://www.medchemexpress.com
50-81-7 manufacturer 113559-13-0 supplier PMID:30085586 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
