Assified according to the cause of ATN as surgical or medical.
Assified according to the cause of ATN as surgical or medical. ATN was categorized as ischemic, septic or nephrotoxic. Patient characteristics were documented at commencement of RRT. Major outcomes (survival and renal status) were determined at discharge and after 1 and 3 years of follow-up. Results The study population was characterized by high age (mean 65 years), excess comorbidity and by extensive organ failure (mean 2.4 failed organs). The overall inhospital, 1-year and 3-year case fatality rates were 47 , 65 and 71 , respectively. All survivors had renal functional recovery without further need of RRT at discharge and only 0.6 progressed to end-stage renal disease after 1 year. After 3 years, 2 of the survivors needed chronic RRT. Conclusions In contrast to the poor inhospital prognosis of critically ill patients with severe ATN, the overwhelming majority of surviving patients become independent from renal replacement therapy. In patients without pre-existing Actinomycin IV chemical information pubmed ID: renal dysfunction, severe chronic renal failure is unusual and the persistent need for maintenance hemodialysis is rare.P278 Acute renal failure prolongs weaning from mechanical ventilation in critically ill patientsJ Vieira, Jr1, I Castro1, S DeMarzo2, A Cuvello-1Neto, R Abdulkader1, D Deheinzelin2 1University of S Paulo, Brazil; 2Hospital do C cer, S Paulo, Brazil Critical Care 2006, 10(Suppl 1):P278 (doi: 10.1186/cc4625) Acute renal failure (ARF) determines a worse prognosis in various medical scenarios. Since the syndrome of ARF can potentially interfere with the weaning from mechanical ventilation (MV), we sought to investigate whether the presence of ARF has any impact on weaning from MV. We studied 140 patients who received invasive MV for at least 48 hours in an oncologic ICU. Exclusion criteria: neurosurgical patients, pulmonary resections or strict endof-life care. ARF definition: at least one value of serum creatinine PubMed ID: (SCr) 1.5 mg/dl during the ICU stay. Patients were divided into ARF (n = 93) and non-ARF groups (NRF, n = 47). Criteria for weaning: PEEP 8 cmH2O, pressure support 10 cmH2O, FiO2 0.4 and spontaneous respiration. Primary endpoint: length of weaning. Secondary endpoints: length of MV, length of stay in ICU, and mortality. Groups were similar regarding age and gender. A higher number of ARF patients had hematological tumors (19.3 vs 6.4 , P = 0.04). The diagnosis of acute respiratory insufficiency (45 vs 44 ) during the ICU stay and the diagnosis of ALI/ARDS as a cause for MV (18.2 vs 10.6 ) did not differ between groups.SAvailable online Renal replacement therapy and bloodstream infections in cardiovascular intensive care patientsTMV Strabelli, DP Cais, MA Ribeiro, CM Andrade, L Yu, SG Lage Heart Institute of S Paulo University School of Medicine, S Paulo, Brazil Critical Care 2006, 10(Suppl 1):P280 (doi: 10.1186/cc4627) Objective To describe bloodstream infection epidemiology in cardiac patients undergoing hemodialysis admitted to ICUs. Methods We analyzed epidemiological data of laboratorialconfirmed bloodstream infection (BSI) episodes occurring in patients undergoing hemodialysis from October 2004 to March 2005. BSI criteria were defined by the Centers for Disease Control and Prevention. The presence of uncuffed, nontunneled, temporary central catheters for hemodialysis and other central venous catheters was daily monitored. BSI episodes were classified as dialysis-related when they occurred within 48 h.

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