Product Name :
Entasobulin
Description:
Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity.
CAS:
501921-61-5
Molecular Weight:
439.89
Formula:
C26H18ClN3O2
Chemical Name:
2-1-[(4-chlorophenyl)methyl]-1H-indol-3-yl-2-oxo-N-(quinolin-6-yl)acetamide
Smiles :
O=C(C1=CN(CC2C=CC(Cl)=CC=2)C2=CC=CC=C21)C(=O)NC1=CC2=CC=CN=C2C=C1
InChiKey:
LJIUXAHLYIPHOK-UHFFFAOYSA-N
InChi :
InChI=1S/C26H18ClN3O2/c27-19-9-7-17(8-10-19)15-30-16-22(21-5-1-2-6-24(21)30)25(31)26(32)29-20-11-12-23-18(14-20)4-3-13-28-23/h1-14,16H,15H2,(H,29,32)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity.|Product information|CAS Number: 501921-61-5|Molecular Weight: 439.89|Formula: C26H18ClN3O2|Chemical Name: 2-1-[(4-chlorophenyl)methyl]-1H-indol-3-yl-2-oxo-N-(quinolin-6-yl)acetamide|Smiles: O=C(C1=CN(CC2C=CC(Cl)=CC=2)C2=CC=CC=C21)C(=O)NC1=CC2=CC=CN=C2C=C1|InChiKey: LJIUXAHLYIPHOK-UHFFFAOYSA-N|InChi: InChI=1S/C26H18ClN3O2/c27-19-9-7-17(8-10-19)15-30-16-22(21-5-1-2-6-24(21)30)25(31)26(32)29-20-11-12-23-18(14-20)4-3-13-28-23/h1-14,16H,15H2,(H,29,32)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 155 mg/mL (352.ISX-3 Autophagy 36 mM; Need ultrasonic).Raltitrexed site |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32391926 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Entasobulin is a indolizine-glyoxylamide based small molecule that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes.|Products are for research use only. Not for human use.|
