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Bioactive compound recovery in the cornelian cherry extracts had been obtained at 60 (v/v). These final results are in great agreement with Dumitracu et al. [15] who reported the highest values for TPC at temperatures upan (Z)-Semaxanib site ethanol concentration in between 500 . The for TPC at temperatures as much as 35 C and to 35 and an ethanol concentration involving 500 . Thethe influence of influence with the independent variables on the TAA (mg TE/g analysis of analysis from the the independent variables on the TAA (mg TE/g dw) and on dw) and on the TPC concentration (mg GAE/g dw)us to receive to good correlation amongst the TPC concentration (mg GAE/g dw) allowed permitted us a obtain a great correlation in between both response parameters1). each response parameters (Figure (Figure 1).35TAA (mg TE/g dw)25 R= 0.986 20 15 10 five 0 0 5 10 15 20 25 30TPC (mg GAE/g dw) (a)35TAA (mg TE/g dw)25 20 15 10 five 0 0.0 0.5 1.0 1.5 2.0 R= 0.TFC (mg QE/g dw) (b)Figure 1. Correlation of TPC (a) and TFC (b) values with all the TAA for the conventional extraction. Figure 1. Correlation of TPC (a) and TFC (b) values using the TAA for the conventional extraction.As anticipated, Figure 1a shows an increase inside the antioxidant activity together with the TPC content of your extracts, as well as together with the TFC content (Figure 1b). The Pearson productmoment correlation among the TAA and also the TPC revealed a statistical correlation in between those two variables (p-value was 0.000, at a 95 self-confidence level; having a correlation coefficient of 0.99), at the same time as in between the TAA along with the TFC (p-value was 0.000, at a 95 self-assurance level; using a correlation coefficient of 0.93). The statistical software allowed us to acquire the F-test ratio, the coefficient of regression two , the R2 adjusted for D.F., the AZD4625 Autophagy Durbin atson statistic, plus the p-values of the predicted RAppl. Sci. 2021, 11,9 ofmodel for the TPC, the TFC, and the TAA from the cornelian cherry standard extracts (Table two).Table 2. F-test ratio, coefficient of regression R2 , Durbin atson statistic and p-values with the predicted model for TPC, TFC and TAA from cornelian cherry conventional extracts. Variables X1 : Temperature X2 : time X3 : Ethanol X1 two X2 two X3 2 X1 X2 X1 X3 X2 X3 R2 adjusted for D.F. R2 Durbin atson statistic TPC (mg GAE/g dw) F-Ratio three.55 22.23 738.six 36.0 32.83 0.91 1.31 0.43 five.54 p-Value 0.1184 0.0053 0.0000 0.0018 0.0023 0.3843 0.3050 0.5413 0.0652 0.9833 0.9941 two.74 (p = 0.844) TFC (mg QE/g dw) F-Ratio 0.15 0.10 206.54 0.63 1.83 22.04 0.33 0.01 1.42 p-Value 0.7129 0.7621 0.0000 0.4626 0.2308 0.0054 0.5899 0.9190 0.2867 TAA (mg TE/g dw) F-Ratio 0.05 21.59 902.40 53.93 50.35 1.46 9.02 0.99 2.92 p-Value 0.8275 0.0056 0.0000 0.0007 0.0009 0.2808 0.0300 0.3648 0.0.9416 0.9791 2.88 (p = 0.919)0.9866 0.9952 two.56 (p = 0.701)The ANOVA table partitions were applied in order to observe the variability in the response variables in separate pieces for each and every on the effects. The test in the statistical significance for every single effect was applied by comparing the mean square against an estimate with the experimental error. In Table 2, it could be observed that inside the case of all three response variables (TPC, TFC and TAA) the quantity of ethanol inside the hydroalcoholic option features a statistically considerable effect (p 0.05), as also described by the Pareto diagram (Figure 2). The model fits the experimental values for the TFC, the TPC, along with the TAA to a great extent as R2 is close to 1 for all the responses, in accordance with Table 2. The Durbin atson statistic tests indicate the re.

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