Domestic processing approaches on chemical composition, in vitro digestibility of protein
Domestic processing strategies on chemical composition, in vitro digestibility of protein and starch and functional properties of bambara groundnut (voandzeia subterranea) seed. Res J Agri Biol Sci three(1):244 Yusuf AA, Mofio BM, Ahmed AB (2007) Nutrient contents of pride of Barbados (Caesalpinia pulcherrima Linn) seeds. Pakistan J Nutr six(2):117doi:10.11862193-1801-3-298 Cite this article as: Andualem and Gessesse: Proximate composition, mineral content material and antinutritional things of Brebra (Millettia ferruginea) seed flour at the same time as physicochemical characterization of its seed oil. SpringerPlus 2014 3:298.
Hosp Pharm 2013;48(four):27479 2013 Thomas Land AChE manufacturer Publishers, Inc. thomasland doi: ten.1310hpj4804-Cancer Chemotherapy Update carboplatin (Renally Dosed) and Etoposide Regimen for Small-Cell Lung CancerMatthew R. Rutledge, RPh, BCOPp; J. Aubrey Waddell, PharmD, FAPhA, BCOP; and Dominic A. Solimando, Jr, MA, FAPhA, FASHP, BCOPThe complexity of cancer chemotherapy demands pharmacists be acquainted with the complex regimens and extremely toxic agents used. This column reviews numerous problems related to preparation, dispensing, and administration of antineoplastic therapy, plus the agents, each commercially out there and investigational, utilised to treat malignant ailments. Inquiries or suggestions for Kainate Receptor manufacturer topics ought to be addressed to Dominic A. Solimando, Jr, President, Oncology Pharmacy Services, Inc, 4201 Wilson Blvd #110-545, Arlington, VA 22203, e-mail: OncRxSvccomcast.net; or J. Aubrey Waddell, Professor, University of Tennessee College of Pharmacy; Oncology Pharmacist, Pharmacy Division, Blount Memorial Hospital, 907 E. Lamar Alexander Parkway, Maryville, TN 37804, e-mail: waddfourcharter.net.Regimen Name: CE Origin of Name: CE is definitely an acronym for the two medicines in the regimen: carboplatin and etoposide. COMMENTS Carboplatin doses are commonly calculated employing equations based on the approach of Calvert et al.1 Calvert’s group showed that the carboplatin dose in milligrams might be calculated using a selected carboplatin area beneath the curve (AUC) and also the patient’s glomerular filtration price (GFR) as determined by clearance of a radiopharmaceutical, chromium-51-EDTA. Calvert’s equation is expressed as carboplatin dosemg five AUC x [GFR 1 25]. A typical practice should be to substitute the GFR from the Calvert equation using a calculated creatinine clearance (CrCl) determined with the Cockcroft-Gault equation. INDICATION(S) The CE regimen has been studied and is advised for primary treatment of both limited and extensive-stage small-cell lung cancer (SCLC) (Table 1).2-DRUG PREPARATION Adhere to institutional policies for preparation of hazardous drugs when preparing carboplatin and etoposide. A. Carboplatin 1. Use carboplatin injection 10 mgmL, or powder for reconstitution. two. Reconstitute the powder to a concentration of ten mgmL with sterile water for injection (SWFI), five dextrose in water (D5W), or 0.9 sodium chloride (NS). three. Dilute with 100 to 1,000 mL of D5W or NS. 4. Carboplatin is significantly less steady in saline options, with up to 5 degradation inside 24 hours.13 five. If the drug is ready within a saline diluent, the option really should be employed inside eight hours. B. Etoposide 1. Use etoposide injection, 20 mgmL. two. Dilute with D5W or NS to a final concentration of 0.two mgmL to 0.4 mgmL. 3. Concentrations greater than 0.four mgmL are not stable and could precipitate in the course of infusion. DRUG ADMINISTRATION A. Carboplatin: Administer by intravenous (IV) infusion more than 30 to 60 min.
