Domestic processing procedures on chemical composition, in vitro digestibility of protein
Domestic processing procedures on chemical composition, in vitro digestibility of protein and starch and functional properties of bambara groundnut (voandzeia subterranea) seed. Res J Agri Biol Sci three(1):244 Yusuf AA, Mofio BM, Ahmed AB (2007) Nutrient contents of pride of Barbados (Caesalpinia pulcherrima Linn) seeds. Pakistan J Nutr 6(two):117doi:10.11862193-1801-3-298 Cite this short article as: Andualem and Gessesse: Proximate composition, mineral content material and antinutritional variables of Brebra (Millettia ferruginea) seed flour as well as physicochemical characterization of its seed oil. SpringerPlus 2014 three:298.
Hosp Pharm 2013;48(four):27479 2013 Thomas Land Publishers, Inc. thomasland doi: ten.1310hpj4804-Cancer Chemotherapy Update Carboplatin (Renally Dosed) and Etoposide Regimen for Small-Cell Lung CancerMatthew R. Rutledge, RPh, BCOPp; J. Aubrey Waddell, PharmD, FAPhA, BCOP; and GLUT2 list Dominic A. Solimando, Jr, MA, FAPhA, FASHP, BCOPThe complexity of cancer chemotherapy requires pharmacists be acquainted with the difficult regimens and very toxic agents utilized. This column testimonials numerous concerns connected to preparation, dispensing, and administration of antineoplastic therapy, as well as the agents, each commercially obtainable and investigational, utilised to treat malignant diseases. Inquiries or recommendations for subjects should be addressed to Dominic A. Solimando, Jr, President, Oncology Pharmacy Solutions, Inc, 4201 Wilson Blvd #110-545, Arlington, VA 22203, e-mail: OncRxSvccomcast.net; or J. Aubrey Waddell, Professor, University of Tennessee College of Pharmacy; Oncology Pharmacist, Pharmacy Department, Blount Memorial mAChR5 Molecular Weight Hospital, 907 E. Lamar Alexander Parkway, Maryville, TN 37804, e-mail: waddfourcharter.net.Regimen Name: CE Origin of Name: CE is definitely an acronym for the 2 medicines in the regimen: carboplatin and etoposide. COMMENTS Carboplatin doses are frequently calculated employing equations primarily based on the approach of Calvert et al.1 Calvert’s group showed that the carboplatin dose in milligrams might be calculated working with a chosen carboplatin area below the curve (AUC) plus the patient’s glomerular filtration rate (GFR) as determined by clearance of a radiopharmaceutical, chromium-51-EDTA. Calvert’s equation is expressed as carboplatin dosemg five AUC x [GFR 1 25]. A frequent practice would be to substitute the GFR of your Calvert equation with a calculated creatinine clearance (CrCl) determined with the Cockcroft-Gault equation. INDICATION(S) The CE regimen has been studied and is recommended for primary remedy of each restricted and extensive-stage small-cell lung cancer (SCLC) (Table 1).2-DRUG PREPARATION Adhere to institutional policies for preparation of hazardous drugs when preparing carboplatin and etoposide. A. Carboplatin 1. Use carboplatin injection ten mgmL, or powder for reconstitution. two. Reconstitute the powder to a concentration of 10 mgmL with sterile water for injection (SWFI), 5 dextrose in water (D5W), or 0.9 sodium chloride (NS). three. Dilute with 100 to 1,000 mL of D5W or NS. four. Carboplatin is much less stable in saline options, with as much as 5 degradation inside 24 hours.13 five. If the drug is prepared within a saline diluent, the solution should really be utilised within eight hours. B. Etoposide 1. Use etoposide injection, 20 mgmL. two. Dilute with D5W or NS to a final concentration of 0.2 mgmL to 0.four mgmL. 3. Concentrations higher than 0.four mgmL usually are not steady and may precipitate through infusion. DRUG ADMINISTRATION A. Carboplatin: Administer by intravenous (IV) infusion over 30 to 60 min.
