Domestic processing strategies on chemical composition, in vitro digestibility of protein
Domestic processing methods on chemical composition, in vitro digestibility of protein and starch and functional properties of bambara groundnut (voandzeia subterranea) seed. Res J Agri Biol Sci 3(1):244 Yusuf AA, Mofio BM, Ahmed AB (2007) Nutrient contents of pride of Barbados (Caesalpinia pulcherrima Linn) seeds. Pakistan J Nutr six(two):117doi:10.11862193-1801-3-298 Cite this short article as: Andualem and Gessesse: Proximate composition, mineral MAO-B manufacturer content material and antinutritional elements of Brebra (Millettia ferruginea) seed flour too as physicochemical characterization of its seed oil. SpringerPlus 2014 3:298.
Hosp Pharm 2013;48(four):27479 2013 Thomas Land Publishers, Inc. thomasland doi: 10.1310hpj4804-Cancer Chemotherapy Update Carboplatin (Renally Dosed) and Etoposide Regimen for Small-Cell Lung CancerMatthew R. Rutledge, RPh, BCOPp; J. Aubrey Waddell, PharmD, FAPhA, BCOP; and Dominic A. Solimando, Jr, MA, FAPhA, FASHP, BCOPThe complexity of cancer chemotherapy needs pharmacists be familiar with the complicated regimens and highly toxic agents utilised. This column reviews a variety of concerns associated to preparation, dispensing, and administration of antineoplastic therapy, along with the agents, each commercially readily available and investigational, used to treat malignant illnesses. Queries or ideas for subjects ought to be addressed to Dominic A. Solimando, Jr, President, Oncology Pharmacy Services, Inc, 4201 Wilson Blvd #110-545, Arlington, VA 22203, e-mail: OncRxSvccomcast.net; or J. Aubrey Waddell, Professor, University of Tennessee College of Pharmacy; Oncology Pharmacist, Pharmacy Division, Blount Memorial Hospital, 907 E. Lamar Alexander CDK2 Formulation Parkway, Maryville, TN 37804, e-mail: waddfourcharter.net.Regimen Name: CE Origin of Name: CE is definitely an acronym for the 2 medicines inside the regimen: carboplatin and etoposide. COMMENTS Carboplatin doses are commonly calculated working with equations based on the technique of Calvert et al.1 Calvert’s group showed that the carboplatin dose in milligrams may be calculated making use of a selected carboplatin area below the curve (AUC) along with the patient’s glomerular filtration rate (GFR) as determined by clearance of a radiopharmaceutical, chromium-51-EDTA. Calvert’s equation is expressed as carboplatin dosemg 5 AUC x [GFR 1 25]. A widespread practice would be to substitute the GFR in the Calvert equation with a calculated creatinine clearance (CrCl) determined with all the Cockcroft-Gault equation. INDICATION(S) The CE regimen has been studied and is suggested for key remedy of both limited and extensive-stage small-cell lung cancer (SCLC) (Table 1).2-DRUG PREPARATION Stick to institutional policies for preparation of hazardous medicines when preparing carboplatin and etoposide. A. Carboplatin 1. Use carboplatin injection 10 mgmL, or powder for reconstitution. two. Reconstitute the powder to a concentration of ten mgmL with sterile water for injection (SWFI), 5 dextrose in water (D5W), or 0.9 sodium chloride (NS). 3. Dilute with 100 to 1,000 mL of D5W or NS. 4. Carboplatin is much less steady in saline solutions, with as much as five degradation inside 24 hours.13 5. When the drug is ready inside a saline diluent, the answer ought to be utilised inside eight hours. B. Etoposide 1. Use etoposide injection, 20 mgmL. two. Dilute with D5W or NS to a final concentration of 0.two mgmL to 0.four mgmL. three. Concentrations greater than 0.4 mgmL usually are not steady and may perhaps precipitate during infusion. DRUG ADMINISTRATION A. Carboplatin: Administer by intravenous (IV) infusion more than 30 to 60 min.
